Journal of Medicinal Materials, 2025, Vol. 30, No. 2 (pp. 80 - 85)

CHEMICAL CONSTITUENT OF THE LEAVESAND STEMS

OF PHARBATIS NIL

Nguyen Thi Kim Oanh^1,2, Do Hoang Anh¹, Nguyen Thi Thu¹, Bui Khac Hieu¹,

Vu Huong Thuy³, Nguyen Duy Thuan⁴, Nguyen Thi Vinh Hue^3,5, Do Thi Ha^1,*

¹National Institute of Medicinal Materials (NIMM), Hanoi, 11022, Vietnam;

²Thai Binh University of Medicine and Pharmacy, Thai Binh, 410000, Vietnam;

³Traphaco Joint Stock Company, Hanoi, 11719, Vietnam;

⁴Vietnam University of Traditional Medicine, Hanoi, 12110, Vietnam

⁵Faculty of Pharmacy, Dainam University, Ha Dong, Hanoi, 12119, Vietnam

*Corresponding author: hado.nimms@gmail.com

Summary

Chemical Constituent of the Leaves and Stems of Pharbatis nil

The phytochemical investigation of the leaves and stems of Pharbatis nil led to the isolation of nine compounds (1–9). The structures of these compounds were determined through 1D- and 2D-NMR spectroscopic analysis, MS, and comparison with published spectroscopic data. The isolated compounds include uracil (1), thymidine (2), ethyl α-L-arabinofuranoside (3), ethyl-β-D-galactofuranoside (4), vitexin (5), β-sitosterol (6), stigmast-4-en-3-one (7), stigmast-4-en-3,6-dione (8), and daucosterol (9). Compounds 2, 4, 5, 7, and 8 were reported for the first time in this species.

Keywords: Pharbatis nil; Pyrimidine derivatives; Sugars; Flavonoid; Sterols.

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