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Nghiên cứu thành phần hóa học của lá cây thiên lý

Nghiên cứu thành phần hóa học của lá cây thiên lý

Summary

Studies on Chemical Composition from the Leaves of Telosma cordata

The methanolic extract from the leaves of Telosma cordata showed in vitro cytotoxic activity against Hep-G2 (heptonema carcinoma), Fl (fibril sarcoma of uterus) and RD (rhabdosarcoma) with the ED values of 39.0%, 12.6% and 5.6%, respectively. Fractionation of the extracts gave compounds belonging to different classes. Four compounds: lutein (1), 1-dotriacontanol (2), 24E-stigmasta-5,22-dien-3b-ol (3), and daucosterol (4) were isolated from the n-hexane extracts. These structures were elucidated by analysis of the NMR data.

Keywords: Telosma cordata, cytotoxic activity, lutein, 1-dotriacontanol, stigmasterol, daucosterol.

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