Journal of Medicinal Materials, 2020, Vol. 25, No. 3 (pp. 146  - 150)

CHEMICAL CONSTITUENTS FROM JATROPHA GOSSYPIIFOLIA L.

Le Quoc Khanh¹, Le Hong Phuc¹, Vo Duc Nhan¹, Dinh Ngoc Thuc²,

Bui Thu Ha³, Le Nguyen Thanh^4,*

¹Hatinh Pharmaceutical Company (HADIPHAR), Vietnam

² Department of Botany, Faculty of Biology, Hanoi National University of Education, Vietnam

³Department of Scientific Management, Hong Duc University, Thanh Hoa, Vietnam

⁴Institute of Marine Biochemistry, VAST, Hanoi, Vietnam

*Corresponding author: lethanh7676@gmail.com

(Received March 18^th, 2020)

Summary

Chemical Constituents from Jatropha gossypiifolia L.

Jatropha gossypiifolia L. (Euphorbiaceae) is used in traditional medicine with a wide range of pharmacological activities. From ethyl acetate extract of Jatropha gossypiifolia leaves and stem, five compounds were isolated by chromatographic techniques. Their chemical structures were identified as acetyl aleuritolic acid (1), ergosterol peroxide (2), altissimanin B (3), 3β,12-dihydroxy-13-methylpodocarpane-8,11,13-triene (4) and gossweilone (5) by NMR, MS spectroscopic data and comparison with the reported literature. Compounds 1-2 and 4-5 were isolated from J. gossypiifolia for the first time.

Keywords: Jatropha gossypiifolia, Triterpene, Sterol, Nor-diterpene.

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