IN VITRO STUDY ON ANTIOXIDANT ACTIVITY OF
POGONATHERUM CRINITUM (THUNB.) KUNTH
Nguyen Hoang Minh, Nguyen Thi Thu Huong*
Research Center of Ginseng and Medicinal Materials in Ho Chi Minh City-
Vietnam National Institute of Medicinal Materials
*Corresponding author: huongsam@hotmail.com
(Received July 25th, 2014)
Summary
In vitro Study on Antioxidant Activity of Pogonatherum crinitum (Thunb.) Kunth
Pogonatherum crinitum (Thunb.) Kunth is a wild grass which has been used in ethnic medical experience for treatment of many inflammatory diseases including urethritis, cystitis, nephritis and hepatitis. There is a little of scientific profiles on P. crinitum until now. The study was performed for primarily screening biological activities of P. crinitum. Antioxidant activities of crude extract and its fractionated extracts (diethyl ether, ethyl acetate and water, successively) were elucidated by using DPPH and malondialdehyde (MDA) assays. The results showed that P. crinitum extracts has both free radical scavenging activity and lipid peroxidation inhibiting activities. In DPPH test, ethyl acetate fraction showed higher activity than crude extract and other fractions. In MDA test, all test extracts exhibited higher antioxidant activity than the positive control Trolox in which diethyl ether fraction had strongest antioxidant activity.
Keywords: Pogonatherum crinitum, Antioxidant activity, DPPH assay, Malondialdehyde (MDA) assay.
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