Journal of Medicinal Materials, 2019, Vol. 24, No. 5 (pp. 264 - 269)
FLAVONOL METHYL ETHERS FROM THE RHIZOMES
OF AMOMUM CELSUM OF VIETNAM
Ta Thi Thuy1, Phan Minh Giang2,*, Mai Thai Son2, Tran Xuan Truc2,
Nguyen Nghia Vu3, Do Thi Viet Huong2
1National Institute of Medicinal Materials (NIMM), Hanoi, Vietnam;
2Faculty of Chemistry, VNU University of Science, Vietnam National University, Hanoi, Vietnam;
3Center for Research and Production of Vaccines and Biologicals, Hanoi, Vietnam
*Corresponding author: firstname.lastname@example.org
(Received May, 23rd, 2019)
Flavonol Methyl Ethers from the Rhizomes of Amomum celsum of Vietnam
Methyl ethers of flavonoids have been known for their role in modulating biological activities of the parent flavonoids; they have also been used as chemotaxonomic markers for plant species. We isolated four compounds 5-hydroxy-3,7,4¢-trimethoxyflavone (1), 5-hydroxy-3,7,3¢,4¢-tetramethoxyflavone (retusin) (2), 5,4¢-dihydroxy-3,7-dimethoxyflavone (kumatakenin) (3), and 3,5-diacetoxy-1,7-bis-(3,4-dihydroxyphenyl)heptane (4) from the rhizomes of Amomum celsum Lamxay & M.F. Newman. The structure elucidation of the isolated compounds was performed on the basis of MS and NMR techniques. Compounds 1 and 3 were isolated for the first time from the plant.
Keywords: Amomum celsum, Methylated flavonol, Kaempferol, Quercetin.
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