Journal of Medicinal Materials, 2020, Vol. 25, No. 3 (pp. 135 - 141)
ISOLATION AND STANDARD ESTABLISHMENT
OF ASTRAGALOSIDE IV FROM RADIX ASTRAGALI MEMBRANACEI
Huynh Tran Quoc Dung1, Phan Thi Thuy Tien2, Pham Ngoc Thac1,
Nguyen Duc Hanh3,*, Nguyen Minh Duc3,4
1Traditional Medicine Hospital, Ho Chi Minh City, Vietnam; 2OPC Pharmaceutical Joint Stock Company, Vietnam;
3Faculty of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam;
4Faculty of Pharmacy, Ton Duc Thang University, Vietnam
*Corresponding author: firstname.lastname@example.org
(Received May 15th, 2020)
Isolation and Standard Establishment of Astragaloside IV from Radix Astragali membranacei
Astragaloside IV is a marker for the quality control of Radix Astragali membranacei. This herbal is used for tonifying Qi and blood. The study aimed to isolate astragaloside IV from Radix Astragali membranacei by using alkaline hydrolysis method and different chromatography techniques such as thin-layer chromatography, column chromatography and preparative high-performance liquid chromatography (HPLC). The isolated compound was established as a reference standard based on ISO Guide 34 and 35. Astragaloside IV (2.0 g) was isolated from 4.0 kg of Radix Astragali membranacei. The adjust content of astragaloside IV was determined to be 96.74%.
Keywords: Radix Astragali membranacei, Astragaloside IV.
(Nguồn tin: )