Journal of Medicinal Materials, 2021, Vol. 26, No. 5 (pp. 271 - 277)

PENNOGENIN, PREGNAN GLYCOSIDES

AND ECDYSTERONE DERIVATIVES FROM THE RHIZOMES

OF PARIS VIETNAMENSIS (TAKHT) H.LI

Nguyen Thi Thu¹, Vu Thi Diep¹, Nguyen Thi Hang¹, Nguyen The Hung²,
Nguyen Minh Khoi¹, Do Thi Ha^1,*

¹National Institute of Medicinal Materials (NIMM), Hanoi, Vietnam; ²Hanoi University of Pharmacy, Vietnam

*Corresponding author: hado.nimms@gmail.com

(Received August 24^th, 2021)

Summary

Pennogenin, Pregnan Glycosides and Ecdysterone Derivatives from the Rhizomes of Paris vietnamensis (Takht) H.Li

Three saponins and two ecdysterone derivatives were isolated from the rhizomes of Paris vietnamensis. The structures of compounds were confirmed by spectroscopic methods (MS and NMR) and comparision with published spectroscopic data, including paris saponin H (1), paris saponin VII (2), 3β,21-dihydroxy-pregnan-5-ene-20S-(22,16)-lactone-1-O-α-L-rhamnopyranosyl(1→2)-[β-D-xylopyranosyl(1→3)]-β-D-glucopyranoside (3), 20-hydroxyecdysterone (4), and 20-hydroxyecdysone 20,22-acetonide (5). Compounds 3 and 4 were first isolated from this species and compound 5 was also reported for the first time in the genus Paris L..

Keywords: Paris vietnamensis, Pennogenin glycosides, Pregnan glycosides, Ecdysterone derivatives.