Journal of Medicinal Materials, 2024, Vol. 29, No. 5 (pp. 265 - 269)

PHENOLIC CONSTITUENTS FROM PROPOLIS

OF STINGLESS BEE TETRIGONILLA COLLINA

Nguyen Thanh Cong^1,2, Trinh Thi Thanh Van³, Diep Thi Lan Phuong⁴, Vassya Bankova⁵,

Nguyen Thu Hang¹, Le Nguyen Thanh^3,6,*

¹Faculty of Pharmacognosy and Traditional Medicine, Hanoi University of Pharmacy, Hanoi, Vietnam;

²Faculty of Pharmacy, Dai Nam University, Hanoi, Vietnam;

³Institute of Marine Biochemistry, Vietnam Academy of Science and Technology, Hanoi, Vietnam;

⁴Faculty of Natural Sciences, Quy Nhon University, Binh Dinh, Vietnam;

⁵Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences,

Acad. G. Bonchev str., bl.9, Sofia, Bulgaria;

⁶Present address: National Institute of Medicinal Materials (NIMM), Hanoi, Vietnam

*Corresponding author: lethanh@imbc.vast.vn

(Received August 02^nd, 2024)

Summary

Phenolic Constituents from Propolis of Stingless Bee Tetrigonilla collina

Phytochemical study of propolis of stingless bee Tetrigonilla collina collected in Kon Ka Kinh forest led to the isolation of six phenolic compounds: siamyl benzoate (1), (+)-pinoresinol (2), coniferyl aldehyde (3), p-coumaraldehyde (4), trans-cinnamic acid (5), and vanillin (6). The structures of isolated compounds 1-6 were elucidated by spectroscopic (NMR and MS) analysis and comparison with the previous data. This is the first chemical investigation of T. collina propolis.

Keywords: Tetrigonilla collina, Lignan, Benzoate, Phenylpropanoid, Phenolic. 

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