Journal of Medicinal Materials, 2024, Vol. 29, No. 3 (pp. 154 - 158)
PHYTOCHEMICAL CONSTITUENTS FROM THE AERIAL PARTS
OF LACTUCA INDICA
Luong Thuy Nhung1†, Vu Thi Oanh 1†, Nguyen Khac Tung2, Phuong Thien Thuong1 ,*
1Vietnam - Korea Institute of Science and Technology, Vietnam;
2Thai Nguyen University of Medicine and Pharmacy, Vietnam
† These authors contributed equally to this study
*Corresponding author: ptthuong@most.gov.vn
(Received May 15th, 2024)
Summary
Phytochemical Constituents from the Aerial Parts of Lactuca indica
From the ethyl acetate-soluble fraction of the aerial parts of Lactuca indica L., seven compounds, including three sesquiterpene lactones (1, 6, and 7), two phenylpropanoids (2 and 3), and two quinic acid derivatives (4 and 5) were isolated by using chromatographic methods (TLC and CC). The structures of compounds (1-7) were elucidated as lactuside B (1), caffeic acid (2), caffeic acid methyl ester (3), 3,4-di-O-caffeoylquinic acid methyl ester (4), 3,5-di-O-caffeoylquinic acid methyl ester (5), 11β,13-dihydrolactucin (6), and cichorioside B (7) by spectroscopic data (1H- and 13C-NMR and ESI-MS). This is the first report on the occurrence of 4 and 5 in the Lactuca genus and 1-3 in L. indica.
Keywords: Lactuca indica, Sesquiterpene lactones, Phenylpropanoids, Quinic acid derivatives.
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