Journal of Medicinal Materials, 2017, Vol. 22, No. 5 (pp. 270 - 275)
TRITERPENE GLYCOSIDES ISOLATED FROM
GYMNEMA SYLVESTRE (RETZ.) R. BR. ex SCHULT.
Hoang Minh Chau1, Pham Ha Thanh Tung2,3, Oh Won Keun3,
Nguyen Thi Bich Thu4,*, Tran Van On2, Tran Minh Ngoc4
1Nam Duoc Jsc.; 2Hanoi University of Pharmacy, 3Korea Bioactive Natural Material Bank,
College of Pharmacy; 4National Institute of Medicinal Materials, Hanoi, Vietnam
*Corresponding author: email@example.com
(Received August, 18th, 2017)
Triterpene Glycosides Isolated from Gymnema sylvestre (Retz.) R. Br. ex Schult.
From the triterpenoid-rich fraction of Gymnema sylvestre (Retz.) R. Br. Ex Schult., one new compound, 3-O-[β-D-xylopyranosyl(1à6)-β-D-glucopyranosyl(1à6)-β-D-glucopyranosyl] oleanolic acid 28-[β-D-glucopyranosyl(1à6)-β-D-glucopyranosyl] ester (1), and two known compounds, 3-O-[β-D-xylopyranosyl(1à6)-β-D-glucopyranosyl(1à6)-β-D-glucopyranosyl] oleanolic acid 28-β-D-glucopyranosyl ester (2) and 3-O-[β-D-glucopyranosyl(1à6)-β-D-glucopyranosyl] oleanolic acid 28-[β-D-glucopyranosyl(1à6)-β-D-glucopyranosyl] ester (3) were isolated. The chemical structure of the new compound was elucidated by the extensive nuclear magnetic resonance (NMR), mass spectrometry (MS) and other spectroscopic techniques; while the structures of the two known compounds were verified by comparing their physicochemical and spectroscopic data to published literature.
Keywords: Gymnema sylvestre, Apocynaceae, Oleanolic acid, Saponin.
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