Journal of Medicinal Materials, 2021, Vol. 26, No. 1+2 (pp. 5 - 9)

TRITERPENES FROM THE STEMS OF ADINANDRA POILANEI GAGNEP.

Vu Thi Kim Oanh¹, Bui Thu Ha², Le Thi Hong Nhung³,

Nguyen Thi Van Anh⁴, Le Nguyen Thanh^1,*

¹Graduate Unversity of Science and Technology and  Institute of Marine Biochemistry, VAST, Hanoi, Vietnam;

²Faculty of Biology, Hanoi National University of Education, Hanoi, Vietnam;

³Hanoi Univesity of Industry, Vietnam;

⁴Hanoi Unversity of Science and Technology, VAST, Hanoi, Vietnam

*Corresponding author: lethanh7676@gmail.com

(Received October 30^th, 2020)

Summary

Triterpenes from the Stems of Adinandra poilanei Gagnep.

Adinandra species have been utilized in Vietnamese folk medicine for the treatment of cancer, stomach aches and snake bite.  From the stems of A. poilanei collected in Lamdong province, six triterpenes were isolated. Their chemical structures were determined as betulinal (1), betulin (2), 3β,20-dihydroxylupane (3), 1-oxo-erythrodiol (4), pirolonic acid (5) and betulinic acid (6). Compounds 3-5 were discovered from Adinandra genus for the first time.

Keywords: Adinandra poilanei, Betulin, 3β,20-dihydroxylupan, 1-oxo-erythrodiol, Pirolonic acid.

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