Summary

Effect of Piper betel L. Leaf Extract on Mouse Model of Atopic Eczema

This research aimed to assess the anti-eczema activity of ethanol extract of Piper betel L. leaves on mouse model of atopic eczema at doses of 1, 2, 4, 6 and 8% (w/v). The effect of ethanol extract of Piper betel L. leaves on mouse model atopic eczema was evaluated by histopathological examination and epidermal thickness. The results showed that the ethanol extract of Piper betel L. leaves at a dose of 4% w/v exhibits the most effective result against eczema in mouse model. These findings provided scientific evidences for the anti-eczema property of the ethanol extract and could be further explored for the treatment of eczema.

Keywords: Eczema, Piper betel L., Histopathological examination, Epidermal thickness, Mouse model.

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