Journal of Medicinal Materials, 2024, Vol. 29, No. 3 (pp. 144 - 149)

NEOLIGNAN, PHENOLS, AND GLYCOSYL COMPOUNDS

FROM THE LEAVES OF BOEHMERIA NIVEA (L.) GAUDICH

Nguyen Thi Thu Thao^{1, 2}, Do Thi Ha³, Tran Dinh Nghia⁴, Truong Quoc Ky⁵, Le Thi Hong Van^1,*

¹Faculty of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam;

²School of Medicine, Vietnam National University Ho Chi Minh City, Vietnam;

³National Institute of Medical Materials (NIMM), Hanoi, Vietnam; ⁴Hanoi University of Pharmacy, Vietnam;

⁵Faculty of Pharmacy, Pham Ngoc Thach University of Medicine, Vietnam

*Corresponding author: levan@ump.edu.vn

(Received May 12^th, 2024)

Summary

Neolignan, Phenol, and Glycosyl Compounds from the Leaves of Boehmeria nivea (L.) Gaudich

Seven compounds belonging to the structures of neolignan, phenols, and glycosyl compounds were isolated from the n-butanol extract of Boehmeria nivea leaves. Their chemical structures were elucidated as glochidioboside (BNL9), protocatechuic acid (BNL1), ethyl β-fructopyranoside (BNL3), eugenyl O-β-apiofuranosyl-(1′′→6′)-O-β-glucopyranoside (BNL10), ethyl α-D-glucopyranoside (BNL11), hydroxytyrosol 4-β-D-glucoside (BNL16), and cimidahurinine (BNL17) on the basis of detailed analysis of the 1D and 2D NMR spectroscopic data in comparison with the literature data. Among them, 6 compounds BNL3, BNL9, BNL10, BNL11, BNL16, and BNL17 were reported for the first time in Boehmeria genus.

Keywords: Boehmeria nivea, Urticaceae, Neolignan, Phenolic glycoside.

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