Journal of Medicinal Materials, 2022, Vol. 27, No. 4 (pp. 218 - 222)

CALCIUM OXALATE CRYSTALLIZING INHIBITION OF EXTRACTS FROM SEVERAL PANDANUS SPECIES IN VIETNAM

Do Hoang Giang¹, Truong Thi Lien¹, Dang Viet Hau¹, Vu Duc Nam¹, Nguyen Thi Thu Thuy², Nguyen Tien Dat^1,*

¹Center for Research and Technology Transfer, Vietnam Academy of Science and Technology;

²Institute of Tropical Medicine, Vietnam - Russia Tropical Center, Vietnam

*Corresponding author: ntdat@ctctt.vast.vn

(Received June 20^th, 2022)

Summary

Calcium Oxalate Crystallizing Inhibition of Extracts from Several Pandanus Species in Vietnam

Plants from the genus Pandanus were used as traditional medicines for urolithiasis treatment. Evaluation of calcium oxalate crystallizing inhibition of 14 extracts from 4 Pandanus species revealed that the extracts from P. nanofrutex and P. amaryllifolius exhibited stronger effects than those of P. odoratissimus and P. tectorius. The chemical quantitation and correlation analysis results indicated that phenolics and flavonoids significantly affect the calcium oxalate crystallizing inhibitory effect. These showed promising results for further investigation of antiurolithiatic compounds from Pandanus species.

Keywords: Pandanus, Phenolic, Flavonoid, Alkaloid, Calcium oxalate.

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