Journal of Medicinal Materials, 2018, Vol. 23, No. 3 (pp. 152 - 157)
CHEMICAL COMPOSITION OF AMALOCALYX MICROLOBUS (SPIRE) PIERRE - (APOCYNACEAE) COLLECTED IN SON LA, VIETNAM
Nguyen Hoang Tuan1,*, Bui Hong Cuong1, Vi Thi Thoi2, Pham Ngoc Khanh1,3
1Hanoi University of Pharmacy, Hanoi, Vietnam;
2Son La Medical College, Vietnam;
3Institute of Natural products Chemistry, Vietnam Academy of Science and Technology, Vietnam
*Corresponding author: firstname.lastname@example.org
(Received March, 30th, 2018)
Chemical Composition of Amalocalyx microlobus (Spire) Pierre - (Apocynaceae)
Collected in Son La Province, Vietnam
From an EtOAc-soluble fraction of the methanol extract from the leaves of Amalocalyx microlobus (Spire) Pierre (Apocynaceae), local name Sơn Đôn, collected in Son La, Vietnam, five compounds including: Luteolin (a flavonoid) (1), luteolin-4'-O-β-glucopyranoside (a flavonoid glycoside) (2), amalogenin A (a pregnen-type sterol) (3), β-sitosterol (4) and daucosterol (5) have been isolated. Their chemical structures were established through spectroscopic evidences including 1D, 2D-NMR and MS data. This is the first report on the chemical composition of the species Amalocalyx microlobus in Vietnam.
Keywords: Amalocalyx microlobus, Luteolin, Amalogenin A, Daucosterol, β-sitosterol, Sơn Đôn.
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