Journal of Medicinal Materials, 2019, Vol. 24, No. 3 (pp.186 - 189)

IN VITRO ANTIOXIDANT AND ANTIDIABETIC ACTIVITIES

OF MORINGA OLEIFERA STEM BARKS

Vivian Lago Abascal¹, Mai Thanh Chung², Ha Quang Thanh², Nguyen Hoang Minh²,

Ly Hai Trieu², Chung Thi My Duyen², Dao Tran Mong², Nguyen Mai Truc Tien²,

Nguyen Nhat Minh², Tran My Tien², Le Văn Minh², Ngo Thi Mai Anh³, Nguyen Thi Thu Huong^2,*

¹Entity Science Technology and Innovation, Finlay Institute, La Habana, Cuba;

²Research Center of Ginseng and Medicinal Materials in Ho Chi Minh City -

National Institute of Medicinal Materials, Hanoi, Vietnam; ³Hanoi Medical University, Vietnam

*Corresponding author: huongsam@hotmail.com

(Received April, 23^rd, 2019)

Summary

In vitro Antioxidant and Antidiabetic Activities of Moringa oleifera Stem Barks

The aqueous and ethanol extracts (45%, 70% and 96% ethanol extracts) from Moringa oleifera stem bark cultivated in Cuba were used for in vitro study. DPPH radical scavenging assay and xanthine oxidase inhibitory assay were applied for study on antioxidant activity. α-Amylase inhibitory assay and α-glucosidase inhibitory assay were applied for study on antidiabetic activity. The results revealed that the extracts of M. oleifera stem bark expressed DPPH radical scavenging activity, xanthine oxidase inhibitory activity and α-glucosidase inhibitory activity. Based on IC₅₀, the aqueous extract and the 45% ethanol extract of M. oleifera stem bark exerted xanthine oxidase inhibitory activity and α-glucosidase inhibitory activity more typical than the others, respectively.

Keywords: Moringa oleifera stem bark, Antioxidant activity, Antidiabetic activity.

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