Journal of Medicinal Materials, 2021, Vol. 26, No. 1+2 (pp. 28 - 34)

LIGNAN DERIVATIVES FROM THE STEM BARK OF

RHIZOPHORA APICULATA BLUME

Pham Thanh Binh¹, Ha Van Oanh², Kieu Thi Phuong Linh¹, Nguyen Van Chien³,

Nguyen Quoc Trung⁴, Vu Huy Thong⁵, Nguyen Van Thanh¹, Nguyen Phuong Thao^1,*

¹Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Vietnam;

²Hanoi University of Pharmacy, Vietnam;

³Institute for Tropical Technology, VAST, Vietnam;

⁴Institute of Materials Science, VAST, Vietnam;

⁵University of Fire Fighting and Prevention, Vietnam

*Corresponding author: thaonp@imbc.vast.vn

(Received December 31^st, 2020)

Summary

Lignan Derivatives from the Stem Bark of Rhizophora apiculata Blume

Using chromatographic separations, eight lignan compounds (1-8), were isolated from an ethyl acetate extract of Rhizophora apiculata Blume stem bark. Their structures were elucidated to be ligballinol (1), (+)-pinoresinol (2), lyciumin (3), salicifoliol (4), (-)-secoisolariciresinol (5), polystachyol (6), isolariciresinol (7), and lyoniside (8) by comprehensive analysis of spectroscopic data (1D, 2D NMR, and mass data) as well as comparison with reported kinds of literatures.

Keywords. Rhizophora apiculata, Rhizophoraceae, Lignan.

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