Journal of Medicinal Materials, 2022, Vol. 27, No. 2 (pp. 86 - 90)

PHENOLIC GLYCOSIDE CONSTITUENTS FROM THE RHIZOMES

OF ATRACTYLODES MACROCEPHALA KOIDZ

Cao Thanh Hai^1,2, Nguyen Thi Luyen³, Pham The Chinh², Ngo Thi Thuy Ngan⁴,

Nguyen Tuong Vy⁵, Nguyen Tien Dat^1,3, Dang Viet Hau^1,3,*

¹Graduate University of Science and Technology, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam;

²Thai Nguyen University of Sciences, Tan Thinh Ward, Thai Nguyen City, Thai Nguyen, Vietnam;

³Center for Research and Technology Transfer, VAST, Hanoi, Vietnam;

⁴Thai Nguyen University of Medicine and Pharmacy, Thai Nguyen, Vietnam;

⁵Hanoi University of Science, Vietnam

*Corresponding author: hauhoahock20@gmail.com

(Received March 25^th, 2022)

Summary

Phenolic Glycoside Constituents from the Rhizomes of Atractylodes macrocephala Koidz

Four compounds were isolated from Atractylodes macrocephala rhizomes as syringin (1), syringaresinol-4-O-b-D-glucoside (2), ent-syringylglycerol-8-O-4′-sinapyl ether 4-O-β-D-glucopyranoside (3), syn-syringylglycerol-8-O-4′-sinapyl ether 4-O-β-D-glucopyranoside (4). Their structures were elucidated by ESI-MS, NMR spectroscopic evidence and in comparison with published data. Compounds 2, 3, and 4 have been isolated from this plant for the first time.

Keywords: Atractylodes macrocephala; Asteraceae; Syringin, Syringaresinol-4-O-b-D-glucoside, Picraquassioside C.

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