Journal of Medicinal Materials, 2021, Vol. 26, No. 1+2 (pp. 19 - 23)
FLAVONOIDS FROM THE LEAVES OF SANCHEZIA NOBILIS HOOK.f.
Bui Thi Xuan1,2,*, Tran Minh Ngoc3, Vu Duc Loi1, Nguyen Minh Khoi2, Tran Thanh Ha2
1VNU School of Medicine and Pharmacy, Vietnam National University, Hanoi, Vietnam;
2National Institute of Medicinal Materials, Hanoi, Vietnam;
3Traditional Medicine Administration, Ministry of Health, Vietnam
*Corresponding author: email@example.com
(Received February 18th, 2021)
Flavonoids from the Leaves of Sanchezia nobilis Hook.f.
Sanchezia nobilis Hook.f. grows mostly in Northern Vietnam, Peru and Ecuador. Its extracts has shown cytotoxicity on MCF-7 cell line, anti-bacterial, anti-fungal, anti-inflammatory and insecticidal activities. S. nobilis has been used in traditional medicine for gastritis treatment in Vietnam. Six flavonoids apigenin (1), kaempferol (2), quercetin (3), afzelin (4), hyperoside (5) and rutin (6) were isolated from the leaves of S. nobilis. The flavonoids 1-6 are described for the first time from the plant species in Vietnam. Compounds 1 and 4 are described for the first time in S. nobilis.
Keywords: Sanchezia nobilis Hook.f., Apigenin, Kaempferol, Quercetin.
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