\n\tSummary

\n\tAma Kong’s remedy, a folk Vietnamese Herbal Formula,

\n\tIncreases Endurance Swimming Capacity of Mice

\n\tAma Kong’s remedy, a folk Vietnamese herbal formula, is used to increase vital energy, and strengthen health and sexual activity. However, its pharmacological effects have not been studied yet. We therefore investigated the effect of an extract of Ama Kong’s remedy on endurance capacity of mice on a set of well-known paradigms. Two paradigms were used: swimming in an adjustable-current water pool or swimming exercise with load. Male Swiss albino mice were given orally either vehicle or Ama Kong’s extract powder (187.5 or 375 mg/kg) for 2 weeks. Mice given Ama Kong’s extract (187.5 or 375 mg/kg) performed an increase in swimming capacity before exhaustion compared with the control mice in both paradigms. This effect was comparable with that in mice given Panax ginseng total saponins (20 mg/kg) as a drug of reference. Our data suggest that Ama Kong’s remedy may have beneficial effects on endurance capacity and could be used as an anti-fatigue and for improving physical stamina.

\n\tKey words: Ama Kong’s remedy; endurance capacity; adjustable-current swimming pool; swimming exercise with load.

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