Evaluation of Antibacterial Activity of Vietnam’s Caesalpinia sappan L.

Ethanol extract of bark of Caesalpinia sappan Linn was examined for its antibacterial activity against Staphyloccocus aureus (S.aureus), Escherichia coli (E. coli) and Salmonella typhi (S. typhi). The assay was carried out by disc diffusion method. S. aureus was the most susceptible strain to the plant extract, followed by S. typhi while Ecoli was resistant to the plant extract. Minimum inhibitory concentration (MIC) test which was done by broth dilution method resulted in the ability to inhibit the survival of S. aureus and S. typhi at 1.6 mg/mL and 2.8 mg/mL, respectively, of plant extract. The phytochemical analysis of tested plant showed the presence of tannins, glycosides, carbohydrates, proteins, steroids and saponins. The study provides available data for further development of producing alternative forms of antibacterial drugs.

Keywords: Caesalpinia sappan L., Escherichia coli, Staphyloccocus aureus, Salmonella typhi, Resistance, Susceptible.

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