Immunostimulating Effects of Leaves and Stems of Callisia fragrans (Lindl.) Woods.
on g-rays Induced Immunosuppressive Model
The present study was undertaken to evaluate the effect of the freeze-dried leaves juice (LVL) and the ethanol-aqueous stems extract (LVT) of Callisia fragrans (Lindl.) Woods. on the immune system of cyclophosphamid-induced immunosuppressed mice. LVL was administrated with the dose of 0.1 and 0.4 g/kg per day and LVT with the dose of 0.023 and 0.092 g/kg per day for 9 days. LVL and LVT both stimulated humoral immunity and cell-mediated immunity: significantly increased the relative weights of spleen and thymus and white blood cells; restored the impairment of the humoral immune response and the cellular immune response in g-rays induced immunosupressed mice (increasing the number of BCD19, TCD3 lymphocytes and the levels of IL-2 and TNF-a in spleen).
Keywords: Callisia fragrans (Lindl.) Woods.; immunostimulating effect.
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