Tạp chí

Cytotoxicity of parthenin, a sesquiterpene isolated from a Crinum species, against some cancer cell lines (Tạp chí Dược liệu, tập 15, số 6/2010)

Cytotoxicity of parthenin, a sesquiterpene isolated from a Crinum species, against some cancer cell lines (Tạp chí Dược liệu, tập 15, số 6/2010)

\n\tSummary

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\n\tCytotoxicity of Parthenin, a Sesquiterpene Isolated from a Crinum Species,

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\n\tAgainst some Cancer Cell Lines

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\n\tPhytochemical study on the ethanol extract of a Crinum species by bioassay-guided fractionation resulted in the isolation of an active principle, which was determined as parthenin (1) on the basis of physicochemical and spectroscopic analyses. This is the first report on the existence of a sesquiterpenoid in a Crinum species. Compound 1 was found to show strong cytotoxic activities against some cancer cell lines.

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\n\tKey words: Crinum, Amaryllidaceae, parthenin, cytotoxicity.

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